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The State of Science is Dire

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Welcome to another Still in the Storm post!

The State of Science is Dire

Over the last 40 years or so we have effectively witnessed the death of science. It is hard to say, but what is currently put forth in most labs bears little resemblance to true science.

Over the next three videos, I am going to share the truth about the current state of science. There are three main issues that I am going to cover. They are:

  1. The fact that most published research findings are more likely to be false than not.

  2. The reproducibility crisis, where upwards of 90% of scientific papers cannot be replicated.

  3. The broken peer review process.

Approximately 18 years ago John Ioannidis put out his now landmark essay entitled, “Why Most Published Research Findings Are False”. In it he outlined a number of factors which, when present, decrease the probability that a given finding is true. The reality is that in most cases many of these factors are present, thus Ioannidis’ conclusion that most findings are false.

This is where I will begin.

Buckle up! We are going for quite a ride…

Let’s Spread the Truth Far and Wide

If you find this information valuable, please help me by liking and sharing the it.

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Until next time, I truly hope you find your still in this storm that is raging all around us. And, of course, don’t stop questioning the science! It is never settled.

Thank you and God Bless.

References:

  1. Ioannidis, J. P. A. (2005). Why Most Published Research Findings Are False. PLOS Medicine, 2(8), e124. https://doi.org/10.1371/JOURNAL.PMED.0020124

  2. Colquhoun, D. (2014). An investigation of the false discovery rate and the misinterpretation of p-values. Royal Society Open Science, 1(3). https://doi.org/10.1098/RSOS.140216

  3. Horton, R. (2015). Offline: What is medicine’s 5 sigma? The Lancet, 385(9976), 1380. https://doi.org/10.1016/S0140-6736(15)60696-1

  4. Moonesinghe, R., Khoury, M. J., & Janssens, A. C. J. W. (2007). Most Published Research Findings Are False—But a Little Replication Goes a Long Way. PLoS Medicine, 4(2), e28. https://doi.org/10.1371/JOURNAL.PMED.0040028


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Authors
Mike Donio, MS